DNA Methyltransferase
wendywilson
A methyl group from S-adenosyl-methionine (SAM) is transferred to the C5 position of the pyrimidine ring of cytosine residues by DNMTs in genomic CpG dinucleotides. CpG dinucleotides are preferentially located in particular regions in the genome, including clusters in gene promoters called CpG islands. https://www.creative-biogene.com/Services/Drug-Discovery-Services/DNA-Methyltransferase-Screening-and-Profiling.html