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Absolute Gene-ius

Jordan Ruggieri, Lisa Crawford

The Applied Biosystems™ Absolute Gene-ius podcast is a fun and informative dive into the molecular methods behind modern biology. Each episode brings scientists and experts together for lively conversations about the technologies, workflows, discoveries, and career stories shaping life science research.

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Episodes

51 episodes

  1. Where qPCR shines – matching the right PCR technology to the experiment 14:56
  2. From biomarker discovery to monitoring – molecular tools for precision oncology 33:50
  3. When the signal is barely there – strategies for rare target detection 18:53
  4. When qPCR says negative – finding IBV with digital PCR 33:31
  5. Better together – how qPCR and dPCR complement each other 21:01
  6. Multiplexing qPCR without multiplying the complexity 38:38
  7. Beyond the band – understanding copy number variation 20:02
  8. qPCR, nested PCR, and the search for bacterial serotypes 32:56
  9. How PCR, CRISPR, and animal models are advancing oncology research 16:20
  10. Genotoxicity, vectors, and the power of integration site analysis 35:15
  11. From brewing to bioprocessing – Steve Lewis on molecular biology trends 22:45
  12. Epigenetics unlocked – how behavior shapes biology 41:41
  13. Multiplexing in action – from simplicity to scientific complexity 19:05
  14. Finding the cheat codes to cell identity 33:18
  15. Science happens, and so do mistakes 14:17
  16. Almost a virus – how AAV powers modern gene therapy 32:59
  17. How sequencing and PCR work together in oncology research 33:08
  18. When PCR gets dirty - tackling PCR inhibitors 11:47
  19. Tracking grape pathogens from air to vine 36:15
  20. Season 4 – new voices, new discoveries 6:27
  21. Digital PCR and the fight against HIV-2 and superbugs 35:11
  22. Biomarkers in motion ― detecting Alzheimer's through saliva 32:34
  23. Python problems – digital PCR takes on the Everglades 34:43
  24. Life finds a way – copy number variation and drug metabolism 35:47
  25. Unlocking cancer’s genetic secrets with digital PCR 33:02
  26. CRISPR, dPCR, and pigs – a cut above the rest 33:55
  27. Season two amplified – reflections and takeaways 13:15
  28. The Poisson perspective – counting out false positives 17:55
  29. Somatic mosaic loss of sex chromosomes and kidney disease 34:19
  30. Automating accuracy – an insider’s view 31:56
  31. Helping democratize access and use of mRNA technology 32:57
  32. Now that’s what I call a high-quality viral vector 32:33
  33. Ch-ch-ch-ch-changes 11:13
  34. What’s your vector, Victor? 35:32
  35. A passion for cfDNA analysis is in her blood 38:56
  36. “Junk” RNA is anything but garbage 33:47
  37. The Bioinformatic artistry behind PCR assay design 34:49
  38. CAR-T loads of immunology insights 32:02
  39. A couple of reproductive biology experts 32:29
  40. Can you handle the Gene-ius? 2:40
  41. An introspective retrospective 30:09
  42. Let’s make a bet – Poisson statistics of digital PCR 36:33
  43. Bioinformatics — the bridge to understanding biology 36:26
  44. PCR on ‘zombie’ organisms in extreme environments 32:39
  45. An Absolute Gene-ius announcement 2:43
  46. Shrimp-ly amazing science 34:49
  47. Raising the fish that spawn our insights 35:53
  48. Avoiding the itch with digital PCR 36:33
  49. Insights from a PCR Whisperer 34:54
  50. Tales of a pandemic PhD 33:54