Mind & Matter
Ozempic Reaches Your Brain in Ways Your Own GLP-1 Can't | Katrin Svensson | 298
1:34:35
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Endogenous peptide diversity, GLP-1 drugs, and methods for novel peptide discovery.
TOPICS DISCUSSED:
Peptide Structure & Production: Short amino acid chains (3-50 residues) cleaved from larger precursors by PCSK enzymes, stored in dense-core vesicles, and released upon stimuli rather than acting as folded enzymes like proteins.
Tissue-Specific Processing: The same precursor…